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Table 6 shows the adverse reactions and symptoms of abstinence in both groups. There were no significant differences between the groups.After 3 months of follow-up after the end of the treatment period, 26.5% of the patients who received nortriptyline and 5.3% patients who received placebo had ceased to smoke (p = 0.0006). Fourteen patients receiving placebo and 20 patients receiving nortriptyline began to smoke again during this follow-up period. Seven patients receiving placebo referred to the presence of depressive symptoms, and 10 patients referred to anxiety symptoms as the cause. All patients receiving nortriptyline referred to anxiety symptoms as the cause.After 6 months'' follow-up from the end of santadamianahabanos2000cigars the treatment period, 20.6% santadamianahabanos2000cigars of patients santadamianahabanos2000cigars who had received nortriptyline and 5.3% of patients who had received placebo had ceased to smoke (p = 0.012). Two santadamianahabanos2000cigars patients who had received nortriptyline began to smoke again at this follow-up period. These patients referred to anxiety symptoms as the cause.